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High Altitude Sickness - Solutions from Genomics, Proteomics and Antioxidant Interventions

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2022


This book reviews the recent advances in the development of proteomics-based biomarkers for the non-invasive diagnosis of altitude sickness and explores the potential of antioxidant therapy for this sickness.

The first chapters introduce the associated pathophysiology and provide mechanistic insights into the enhanced generation of reactive oxygen and nitrogen species (RONS), which leads to an increase in oxidative damage to lipids, proteins, and DNA.

The book then highlights the current problems relating to the diagnosis and treatment of altitude sickness and summarizes novel approaches for identifying potential biomarkers and therapeutics. Lastly, it explores the therapeutic efficacy of antioxidant agents.

Reviews the pathophysiology associated with altitude sickness

Highlights the proteomic-based biomarkers for non-invasive diagnosis of altitude sickness

Provides mechanistic insights into oxidative stress and proteomic alteration in altitude sickness
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