Modern CNS Drug Discovery
Reinventing the Treatment of Psychiatric and Neurological Disorders
| Auflage | 2022 |
| Seiten | 283 pp., 54 illus., 50 tab. |
| Verlag | Springer |
| ISBN | 9783030623531 |
| Artikel-Nr. | 620596 |
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Produktbeschreibung
This textbook provides a comprehensive overview of the currently used concepts, approaches and technologies in the discovery and development of new treatments for the full spectrum of disorders of the central nervous system. It guides the reader through all essential steps, from finding an innovative idea, to the registration of a new drug.
Divided into four sections, the book starts by presenting a broad perspective on current approaches in central nervous system (CNS) drug discovery. The second section addresses the generation of ideas for the identification of targets and novel treatment strategies; covers core functions in early discovery, and provides an example of a novel treatment paradigm: brain stimulation. The third section highlights strategies and technologies in translational CNS drug discovery. In an effort to bridge the gap between discovery and clinical development, it also covers brain imaging, EEG and cognitive testing approaches. The fourth section extensively discusses the clinical phase of drug development, covering the basics of early clinical testing for psychopharmacological drugs. The book’s final chapter addresses the registration for newly developed drugs.
Written by experts from academia and industry, the book covers important basics and best practices, as well as recent developments in drug discovery. Offering in-depth insights into the world of drug development, it represents essential reading for early researchers who want to prepare for a career in drug discovery in academia or industry.
Provides unique perspectives from scientists in both academia and industry on how a new model for discovering drugs for brain disorders is currently emerging
Presents a comprehensive overview of the currently used technologies, approaches and concepts in drug discovery for a full spectrum of disorders of the central nervous system
Pursues an unbiased and truth-seeking approach that allows students and professionals to develop their own vision of drug discovery, which they can use to guide their activities in this field
Divided into four sections, the book starts by presenting a broad perspective on current approaches in central nervous system (CNS) drug discovery. The second section addresses the generation of ideas for the identification of targets and novel treatment strategies; covers core functions in early discovery, and provides an example of a novel treatment paradigm: brain stimulation. The third section highlights strategies and technologies in translational CNS drug discovery. In an effort to bridge the gap between discovery and clinical development, it also covers brain imaging, EEG and cognitive testing approaches. The fourth section extensively discusses the clinical phase of drug development, covering the basics of early clinical testing for psychopharmacological drugs. The book’s final chapter addresses the registration for newly developed drugs.
Written by experts from academia and industry, the book covers important basics and best practices, as well as recent developments in drug discovery. Offering in-depth insights into the world of drug development, it represents essential reading for early researchers who want to prepare for a career in drug discovery in academia or industry.
Provides unique perspectives from scientists in both academia and industry on how a new model for discovering drugs for brain disorders is currently emerging
Presents a comprehensive overview of the currently used technologies, approaches and concepts in drug discovery for a full spectrum of disorders of the central nervous system
Pursues an unbiased and truth-seeking approach that allows students and professionals to develop their own vision of drug discovery, which they can use to guide their activities in this field