The Kappa Opioid Receptor
| Auflage | 2022 |
| Seiten | 350 pp., 100 illus. |
| Verlag | Springer |
| ISBN | 9783030890735 |
| Artikel-Nr. | 619018 |
Noch nicht erschienen, ca. Dez. Liefertermin 1-3 Tage nach Erscheinen
Produktbeschreibung
This book covers the latest knowledge in structure, signaling, and biochemical pharmacology of KOR as well as preclinical research and clinical applications (including clinical phase studies and approved for human use) of KOR compounds. It is divided up into the three parts: Molecular aspects of KOR, Preclinical research on pharmacology of KOR agonists and antagonists in animals and KOR agonists and antagonists in clinical use and in past and present clinical trials.
The chapters "Biosensors monitor ligand-selective effects at kappa opioid receptors" and "The role of dynorphin and the kappa opioid receptor in schizophrenia and major depressive disorder: a translational approach" of this book are available open access under a Creative Commons Attribution 4.0 International License via link.springer.com
Provides recent advances in kappa opioid receptor (KOR) structure and signaling
Highlights advancements in preclinical research on KOR agonists and antagonists in experimental animal models
Summarizes development of KOR agonists/antagonists for clinical use (chronic itch, substance abuse, psych. diseases)
The chapters "Biosensors monitor ligand-selective effects at kappa opioid receptors" and "The role of dynorphin and the kappa opioid receptor in schizophrenia and major depressive disorder: a translational approach" of this book are available open access under a Creative Commons Attribution 4.0 International License via link.springer.com
Provides recent advances in kappa opioid receptor (KOR) structure and signaling
Highlights advancements in preclinical research on KOR agonists and antagonists in experimental animal models
Summarizes development of KOR agonists/antagonists for clinical use (chronic itch, substance abuse, psych. diseases)
