Orthobiologics

This book presents the evidence related to use of injectable biologics to provide faster and better healing for musculoskeletal lesions. It discusses the rationale of various approaches, such as blood derivatives and cell concentrates, applied to lesions of muscles, ligaments, tendons, bones, meniscus and cartilage. On the basis of the most up-to-date literature, the authors explore both the potential and limitations of this minimally invasive and promising treatment.

The first section is devoted to the formulations and rationale of several injectable orthobiologics, while the second section presents current evaluation methods applied to specific joints and pathologies - from tendinopathies through non-unions to osteoarthritis - as well as the results. The third section explores future perspectives, such as pluripotent stem cells, gene therapy and the stimulation of intrinsic stromal cell niches.

Appealing to a broad readership this book is of interest to orthopedists, sports physicians, physiatrists and regenerative medicine experts.

Provides a comprehensive overview of the available orthobiologics treatments

Adopts a clinically oriented approach with a focus on injectable orthobiologics

Presents both the potential and limitations based on the latest literature