Autophagy Regulation of Innate Immunity

This book discusses novel concepts and discoveries concerning the regulation of innate immunity by autophagy and autophagy-related proteins. In the past decade, there have been major advances in our understanding of the molecular mechanisms of autophagy and its physiological functions. This book highlights emerging studies on the underlying mechanisms of autophagy regulation of innate immunity, including inflammation, antiviral immunity and anti-bacterial responses and the signaling pathways that prompt or inhibit the initiation and progression of related diseases. It also offers new ideas and strategies for future drugs based on manipulating autophagy, especially selective autophagy mediated by cargo receptors. Providing a comprehensive overview of the autophagy regulation of innate immunity, it is a valuable resource for graduate students and researchers in the fields of immunology, cell biology and translational medicine.

Focusing on the crosstalk between autophagy and immune regulation

Highlighting emerging studies about the underlying mechanisms of autophagy regulation of innate immunity

Providing with an overall picture of the network of autophagy regulation of innate immunity

Offering new ideas and strategies for future drug design against immunological diseases by manipulating autophagy