IschemiRs: MicroRNAs in Ischemic Stroke

There has been an enormous increase in information relating to microRNA (miRNA) and its strategic role in numerous diseases. This book reviews the emerging role of microRNAs in cerebral ischemia, providing comprehensive details of the links between this small RNA molecule and ischemic stroke, the more prevalent of the two main types of stroke. The chapters address questions relating to microRNA’s function in various pathological features of stroke, like oxidative stress, excitotoxicity and cell death, as well as its role as a biomarker and diagnostic agent, and the current therapeutic interventions. Further, the book highlights the latest research on how miRNAs contribute to neuroregeneration following stroke, discussing the myriad computational tools and databases used in miRNA research, and decsribes how how miRNA modulates other cerebrovascular diseases. The book concludes with fresh insights into the effect of long non-coding RNA in cerebral ischemia.

Features a comprehensive compilation of up-to-date research highlights, covering the central role of microRNA in all aspects of ischemic stroke, from pre to post stroke
Presents bioinformatics tools and databases related to miRNA widely used in ischemic stroke research.
Highlighting features of miRNA in various cerebrovascular diseases
Provides insights into role of this small non-coding RNA in shaping stroke research