In this book, world-renowned experts in the field of hematopoietic cell transplantation examine a range of issues and controversies relating to apheresis, with the aim of identifying current best practices. Readers will find up-to-date guidance on donor evaluation, stem cell mobilization strategies, choice of apheresis device, anticoagulation techniques in apheresis, the role of prediction algorithms in assessing donor eligibility, and the prevention and management of complications. Applications of apheresis devices in the processing of bone marrow grafts are discussed, and detailed attention is devoted to the indications and rationale for therapeutic apheresis procedures, with individual chapters focusing on therapeutic plasma exchange and immunoadsorption, red cell exchange, and extracorporeal photopheresis. Finally, the application of apheresis in pediatric donors and in resource-limiting environments is considered. This book, featuring numerous helpful tables, algorithms, and figures, will be of high practical value for all residents, fellows, and faculty members involved in hematopoietic cell transplantation.