Neuroendocrine tumors (NETs) rank among the most prevalent malignancies of the digestive tract. The indolence of digestive NETs often leads to their only being discovered at advanced stages, resulting in multiple liver metastases. Although surgical resections may successfully treat localized diseases, advanced stages require complex multimodal care. Centers of excellence in the management of NET employ a variety of approaches, from liver directed therapies and symptomatic approaches to using systemic chemotherapy and targeted agents to slow tumor progression, achieving sustainable survival while preserving quality of life. This book has been written by international experts in the field, providing an overview of treatments currently used for patients with digestive NETs. It is intended for gastroenterologists, medical oncologists, endocrinologists, surgeons, nuclear medicine specialists, radiotherapists, scientists, medical school and graduate students working in the area of endocrine tumors.