Autophagy in Health and Disease

Autophagy in Health and Disease, Second Edition provides a comprehensive overview of the process of autophagy and its impact on human physiology and pathophysiology. The book covers the history, trajectory of the research field, mechanisms of autophagy, and its regulation, developmental aspects, including stem cells, embryogenesis, hematopoiesis and paligenosis and focus on several systems, including  Metabolic control and Diabetes, Cardiovascular, Nervous, Immune, Gastrointestinal, and Skeletal. The final chapters provide additional disease considerations, covering cancer, longevity, disease mechanisms, and the therapeutic targeting of autophagy. This book is invaluable to anyone looking for a broader understanding of autophagy outside their specific field.

• Provides a comprehensive overview of the process of autophagy and its impact on human physiology and pathophysiology
• Presents extended coverage of the mechanisms mediating autophagy
• Includes the role of autophagy in stem cells and iPSCs, as well as the regenerative process of 'paligenosis”
• Focuses on new topics in this edition, including Metabolic Control and Diabetes (liver, adipose, pancreas, and skeletal muscle), the nervous system, neurodegeneration, cancer and cancer therapeutics