This book covers the properties of biomaterials that have found wide clinical applications, while also reviewing the state-of-the-art in the development towards future medical applications, starting with a brief introduction to the history of biomaterials used in hip arthroplasty.
The book then reviews general types of biomaterials - polymers, ceramics, and metals, as well as different material structures such as porous materials and coatings and their applications - before exploring various current research trends, such as biodegradable and porous metals, shape memory alloys, bioactive biomaterials and coatings, and nanometals used in the diagnosis and therapy of cancer.
In turn, the book discusses a range of methods and approaches used in connection with biomaterial properties and characterization - chemical properties, biocompatibility, in vivo behaviour characterisation, as well as genotoxicity and mutagenicity - and reviews various diagnostic techniques: histopathological analysis, imagining techniques, and methods for physicochemical and spectroscopic characterization.
Properties of stent deployment procedures in cardiovascular surgeries, from aspects of prediction, development and deployment of stent geometries are presented on the basis of novel modelling approaches.
The last part of the book presents the clinical applications of biomaterials, together with case studies in dentistry, knee and hip prosthesis. Reflecting the efforts of a multidisciplinary team of authors, gathering chemical engineers, medical doctors, physicists and engineers, it presents a rich blend of perspectives on the application of biomaterials in clinical practice. The book will provide clinicians with an essential review of currently available solutions in specific medical areas, also incorporating non-medical solutions and standpoints, thus offering them a
broader selection of materials and implantable solutions.
This work is the result of joint efforts of various academic and research institutions participating in WIMB Tempus project, 543898-TEMPUS-1-2013-1-ES-TEMPUS-JPHES, 'Development of Sustainable Interrelations between Education, Research and Innovation at WBC Universities in Nanotechnologies and Advanced Materials where Innovation Means Business', co-funded by the Tempus Programme of the European Union.
Fatima Zivic is an Assistant Professor at the Faculty of Engineering, University of Kragujevac, Serbia, where she teaches courses on: Biomaterials, Surface Modification Technologies, Metrology and Quality Control. Her research explores novel biomaterial structures and material characterisation (mechanical and structural properties).
Saverio Affatato is a Medical Physicist at the Rizzoli Orthopaedic Institute (IOR) (www.ior.it/tecno). In addition, he is the Head of the 'Wear Characterization of Joint Prostheses Research Unit' of the IOR's Medical Technology Laboratory.
Miroslav Trajanovic is a Full Professor at the Faculty of Mechanical Engineering, University of Nis, Serbia. He has more than 35 years of experience in the application of ICT in mechanical engineering and medicine and more than 250 published papers to his credit. He has broad expertise in the modeling of biomaterials' structural design (scaffold structures,
bone grafts). In addition, he is the Serbian coordinator of the European EURAXESS services network.
Matthias Schnabelrauch received his PhD in Polymer Chemistry from Friedrich-Schiller-University, Jena. After postdoctoral positions at the University of Zurich, ETH Zurich, and the Hans-
Knöll-Institute, Jena, he currently heads the Biomaterials Department of INNOVENT e. V., Jena, Germany. His main research interests are in the synthesis, characterisation and application of degradable biomaterials. He is the author/co-author of more than 150 peer-reviewed scientific papers and 50 patent applications.
Nenad Grujovic is a Full Professor and Head of the Center for Information Technologies (http://cit.fink.rs) at the Faculty of Engineering, University of Kragujevac, Serbia. His research focuses on custom-made medical implants, tissue engineering, 3D printing and FEM modeling. He has led two clinical projects on custom-made implants used i
ont> of Ti-reinforced PMMA artificial ribs (in 2017) made using 3D printing.
Kwang Leong Choy is a Professor of Materials Discovery at University College London and Director of the UCL Institute for Materials Discovery (http://www.ucl.ac.uk/institute-for-materials-discovery). She has authored over 220 peer-reviewed publications, including 3 books, and holds 20 patents on nanomaterials, thin films and coatings for structural, functional and biomedical applications.