This book details the advances in cardiac MRI that have enabled quantitative tissue characterization of the myocardium using the measurements of myocardial and blood T1. Reliable detection of diffuse pathological process in both the cardiomyocytes and the interstitial cells of the myocardium are possible. Evaluation of the native myocardial and interstitial fibrosis and measurements of the extracellular volume fraction has allowed an unprecedented opportunity to elucidate the pathology, diagnosis, and prognosis of cardiovascular disease.
T1-Mapping in Myocardial Disease: Principals and Applications reviews a wide spectrum of significant cardiovascular diseases and provides relevant guidance for clinical implementation of this innovative technique. The specific topics include principles of T1-mapping in cardiovascular diseases and role of T1 mapping in the following diseases: hypertensive heart disease and hypertrophic cardiomyopathy, cardiotoxicity from cancer treatment, cardiac fibrosis, left ventricular hypertrophy in aortic stenosis, peri-infarct injury in ischemic cardiomyopathy, and stem cell therapy. This comprehensive coverage of the utility of T1-map in cardiovascular diseases will greatly appeal to the entire cardiovascular medicine and imaging communities.