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Diagnostic Pathology: Familial Cancer Syndromes

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Print-Ausgabe

2013


Diagnostic Pathology: Familial Cancer Syndromes features a comprehensive review of the top 56 inherited tumor syndromes associated with neoplasms, which every surgical pathologists diagnoses in their daily sign-out practice. With over 175 chapters and written by well-known experts in the field, this book seeks to help surgical pathologists, clinicians, fellows, and residents understand the critical differences in diagnosing familial tumors and differentiating these from the sporadic counterpart. Besides the well-described pathology of these syndromes, the clinical implications on diagnosing these syndromes are also presented in detail. This book will guide pathologists and clinicians to master diagnostic criteria when diagnosing tumors associated with inherited tumor syndromes.

The chapters are organized in three parts:

- The first part, 'Overview of Syndromes' has the detailed description of the major syndromes within 56 chapters, genes involved, associated tumors, and diagnostic criteria. This part also contains tables that may be helpful in better classifying the diseases and the associated syndromes. Each syndrome described includes all benign and malignant tumors occurring in that specific syndrome including the differential diagnosis.

- The second part, 'Syndromes By Specific Diagnosis', discusses in detail, the diseases occurring within the syndromes described in part one. The diagnoses are conveniently grouped according to the gland/organ/tissue involved. Distinct diseases are described by highlighting the characteristics of the tumors according to the different syndromes in which they occur. The book describes in detail some of the distinct characteristics of tumors found in inherited tumor syndromes that distinguishes these tumors from tumors in a sporadic setting. Each diagnosis includes definitions, terminology, etiology, pathogenesis, demographics, clinical presentations, therapy, prognosis, gross and microscopic pathology, differential diagnoses, and special studies including immunohistochemistry and molecular/genetics. Every diagnosis is discussed in concise, bulleted text that highlights the most diagnostically significant factors.

- The third part is 'Syndromes by Organ Location'. This is also divided by organ/subspecialty and distributed among 40 chapters. This part has tables with 'easy-to-find' possible syndromes by organ, with numerous tables including the differential diagnosis. Augmenting the text discussion are numerous gorgeous medical images, including clinical images, gross pathology, histology, and a wide range of special and immunohistochemical stains. Each image is carefully annotated to highlight the most diagnostically significant factors.

Finally, this book features the classic benefits of all Amirsys® titles, including time-saving bulleted text, key facts in each chapter, stunning annotated images, extensive index, and Amirsys eBook Advantage, an online version of the print book with larger images and fully searchable text.

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