The volumes included in Antimicrobial Drug Resistance Handbook represent the first comprehensive, multidisciplinary reference covering the area of antimicrobial drug resistance in bacteria, fungi, viruses, and parasites from basic science, clinical, and epidemiological perspectives.
The first volume, Antimicrobial Drug Resistance Handbook, Mechanisms of Drug Resistance, is dedicated to the biological basis of drug resistance and effective avenues for drug development. With the emergence of more drug-resistant strains, the approach to dealing with the drug resistance problem must include the research of different aspects of the mechanisms of bacterial resistance and the dissemination of resistance genes as well as research utilizing new genomic information. These approaches will permit the design of novel strategies to develop new antibiotics and preserve the effectiveness of currently available ones.
The second volume, Antimicrobial Drug Resistance Handbook, Clinical and Epidemiological Aspects, is devoted to the clinical aspects of drug resistance. Although there is evidence that restricted use of a specific antibiotic can be followed by a decrease in drug resistance to that agent, drug resistance control is not easily achieved. Thus, the infectious disease physician requires input from the clinical microbiologist and infection control specialist to make informed choices for the effective treatment of various strains of drug-resistant pathogens in individual patients.
These volumes are an important reference for students in microbiology, infectious disease physicians, medical students, basic scientists, drug development researchers, microbiologists, epidemiologists, and public health practitioners.